WG3

Feeding strategy to maintain/restore the gut homeostasis.

Diet composition and feeding strategy both plays important roles in the development and establishment of the gut microbiota in terms of function and composition. They provide the opportunity to manage the risk associated with inheriting a genetic predisposition to a particular infection (e.g. adhesion determinant) without the use of antibiotics. There is a lack of understanding of the mechanisms that underlie these effects and this remains a pre-requisite if there possible benefits are to be developed in a practical “on-farm” solution. In this WG the attention will be focused on the tasks listed below:

  •  Reviewing the literature on the impact of different feeding strategies such as: use of protein sources, level of amino acids, dietary fibre sources and levels, application of feed technology, use of fermented liquid feed and the potential of established and new feed additives to control the gut ecosystem, and performing a meta-analysis on the available information. Pre- and probiotic interventions will also be evaluated considering their important role in immune/physiological/metabolomic responses.
  •  Discussing the experimental protocols and parameters to be considered during the study regardless of the manipulation of the gut microbiota using different categories of feed or additives.
  •  Providing data from the PiGutNet participants on new feeding strategies and their impact on gut homeostasis with special attention to the microbial profile and immune function of the gut as well as the effects on the production of metabolites.
  •  Discussing new approaches related to the induction of precocious maturation of the GIT mucosa, to improve GIT health and function.